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MicroRNAs in normal and malignant hematopoiesis

6 Jun 2008

Abstract excerpt

PURPOSE OF REVIEW: The discovery of a novel class of gene regulators, named microRNAs, has changed the landscape of human genetics. In hematopoiesis, recent work has improved our understanding of the role of microRNAs in hematopoietic differentiation and leukemogenesis. RECENT FINDINGS: Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223,...

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PMID: 18536574
DOI: 10.1097/moh.0b013e328303e15d

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