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Uncovering the invisible giant: Amyloid beta plaques and their proposed association with waste removal in Alzheimer-affected human hippocampus

2026-04-30

Abstract excerpt

<title>Abstract</title> <p>According to the prevalent ‘Amyloid Hypothesis,’ the underlying cause for neurodegeneration in Alzheimer Disease (AD) is attributed to the accumulation of misfolded Amyloid ß and tau protein in the form of extracellular sticky plaques and neurofibrillary tangles, respectively. These protein accumulations are thought to be caused by impaired waste removal. In an alternative hypothesis, w...

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Literature Corpus work
3d494f1c-97ab-5bd7-8033-a61bc368e67a
DOI
10.21203/rs.3.rs-9337412/v1
Open publication

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