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Article

Attenuation of cerebral edema facilitates recovery of glymphatic system function after status epilepticus.

JCI insight - 8 Sept 2021

Liu Kewei, Zhu Juan, Chang Yuan, Lin Zhenzhou, Shi Zhu, Li Xing, Chen Xing, Lin Chuman, Pan Suyue, Huang Kaibin

Abstract excerpt

Status epilepticus (SE) is a neurological emergency usually accompanied by acute cerebral edema and long-term cognitive impairment, and is characterized by neurodegeneration and aberrant hyperphosphorylated tau protein (p-tau) aggregation. The glia-lymphatic (glymphatic) system plays a central role in facilitating the clearance of metabolic waste from the brain, but its relationship with cerebral edema and...

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PMID: 34494549
DOI: 10.1172/jci.insight.151835
PMCID: PMC8492308

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