Article
Mouse mutagenesis and disease models for neuropsychiatric disorders.
Current topics in behavioral neurosciences - 1 Jan 2011
Gondo Yoichi, Murata Takuya, Makino Shigeru, Fukumura Ryutaro, Ishitsuka Yuichi
Abstract excerpt
In this chapter, mutant mouse resources which have been developed by classical genetics as well as by modern large-scale mutagenesis projects are summarized. Various spontaneous and induced mouse mutations have been archived since the rediscovery of Mendel's genetics in 1900. Moreover, genome-wide, large-scale mutagenesis efforts have recently been expanding the available mutant mouse resources. Forward genetics...
Topics
- Animals
- Ethylnitrosourea
- Humans
- Mice
- Mice, Transgenic
- Mutagenesis
- Phenotype