Article
Mice deleted for the DiGeorge/velocardiofacial syndrome region show abnormal sensorimotor gating and learning and memory impairments.
Human molecular genetics - 1 Nov 2001
Paylor R, McIlwain K L, McAninch R, Nellis A, Yuva-Paylor L A, Baldini A, Lindsay E A
Abstract excerpt
Del22q11 syndrome is caused by heterozygous deletion of an approximately 3 Mb segment of chromosome 22q11.2. Children diagnosed with del22q11 syndrome commonly have learning difficulties, deficits of motor development, cognitive defects and attention deficit disorder. They also have a higher than normal risk for developing psychiatric disorders, mainly schizophrenia, schizoaffective disorder and bipolar disorder....
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