Article
Insights into immune evasion of human metapneumovirus: novel 180- and 111-nucleotide duplications within viral G gene throughout 2014-2017 seasons in Barcelona, Spain.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2020
Piñana Maria, Vila Jorgina, Maldonado Carolina, Galano-Frutos Juan José, Valls Maria, Sancho Javier, Nuvials Francesc Xavier, Andrés Cristina, Martín-Gómez María Teresa, Esperalba Juliana, Codina Maria Gema, Pumarola Tomàs, Antón Andrés
Abstract excerpt
BACKGROUND: Human metapneumovirus (HMPV) is an important aetiologic agent of respiratory tract infection (RTI). This study aimed to describe its genetic diversity and clinical impact in patients attended at a tertiary university hospital in Barcelona from the 2014-2015 to the 2016-2017 seasons, focusing on the emerging duplications in G gene and their structural properties. METHODS: Laboratory-confirmed HMPV were...
Topics
- Adult
- Child
- Genetic Variation
- Humans
- Immune Evasion
- Infant
- Metapneumovirus
- Nucleotides
- Paramyxoviridae Infections