Article
Association between human leukocyte antigen class II (HLA-DRB and -DQB) alleles and outcome of exposure to Mycobacterium tuberculosis: a cross-sectional study in Nairobi, Kenya.
The Pan African medical journal - 1 Jan 2022
Odera Susan, Mureithi Marianne, Aballa Andrew, Onyango Noel, Kazungu Samwel, Ogolla Simon, Kaiyare George, Anzala Omu, Oyugi Julius
Abstract excerpt
Introduction: human leukocyte antigen (HLA) class II alleles play an important role in the early immune response to tuberculosis (TB) by presenting antigenic peptides to CD4+ T cells, hence polymorphisms in those genes can influence the efficiency of the immune response to infection and progression to active disease. Methods: an analytical cross-sectional study of adult pulmonary tuberculosis (PTB) patients at...
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