Article
Identification of HLA-A*11:01-restricted Mycobacterium tuberculosis CD8(+) T cell epitopes.
Journal of cellular and molecular medicine - 1 Sept 2016
Liu Su-Dong, Su Jin, Zhang Shi-Meng, Dong Hai-Ping, Wang Hui, Luo Wei, Wen Qian, He Jian-Chun, Yang Xiao-Fan, Ma Li
Abstract excerpt
New vaccines are needed to combat Mycobacterium tuberculosis (MTB) infections. The currently employed Bacillus Calmette-Guérin vaccine is becoming ineffective, due in part to the emergence of multidrug-resistant tuberculosis (MDR-TB) strains and the reduced immune capacity in cases of HIV coinfection. CD8(+) T cells play an important role in the protective immunity against MTB infections, and the identification...
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