Article

Spatial transcriptomics reveal pitfalls and opportunities for the detection of rare high-plasticity breast cancer subtypes

2023-04-28

Abstract excerpt

Breast cancer is one of the most prominent types of cancers, in which therapeutic resistance is still a major clinical hurdle. Specific subtypes like Claudin-low (CL) and metaplastic breast cancers (MpBC) have been associated with high non-genetic plasticity, which can facilitate resistance. The overlaps and differences between these orthogonal subtypes, respectively identified by molecular and histopathological a...

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Literature Corpus work: 3cb56084-b11d-5c99-b626-1c4dff2cb80c
DOI: 10.1101/2023.04.24.538061

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