Article

<i>De novo</i> -designed minibinders expand the synthetic biology sensing repertoire

2024-01-15

Abstract excerpt

Synthetic and chimeric receptors capable of recognizing and responding to user-defined antigens have enabled “smart” therapeutics based on engineered cells. These cell engineering tools depend on antigen sensors which are most often derived from antibodies. Advances in the de novo design of proteins have enabled the design of protein binders with the potential to target epitopes with unique properties and faster...

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Identifiers and source

Literature Corpus work: 3c5e2907-7955-5c39-82e8-73f28173fa13
DOI: 10.1101/2024.01.12.575267

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