Article

Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus

2022-02-22

Abstract excerpt

<h4>Background</h4> Dysregulation of brain fluid homeostasis associates with brain pathologies in which fluid accumulation leads to elevated intracranial pressure. Surgical intervention remains standard care, since specific and efficient pharmacological treatment options are limited for pathologies with disturbed brain fluid homeostasis. Such lack of therapeutic targets originates, in part, from the incomplete ma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c2ee72f-973c-52c0-ba8b-46af0cdb183a
DOI: 10.1101/2022.02.21.481301

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexusDOI 10.1101/2022.02.21.481301Read

A cellular and spatial map of the choroid plexus across brain ventricles and agesSemantic proximity Read

Transcriptomic profiling of cerebrospinal fluid predicts shunt surgery responses in patients with Normal Pressure HydrocephalusSemantic proximity Read

Multi-omic analysis elucidates the genetic basis of hydrocephalusSemantic proximity Read

Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasisSemantic proximity Read

A Multi-omic Atlas of Human Choroid Plexus in Alzheimer’s DiseaseSemantic proximity Read

Choroid plexus sex differences in secretory signalling and immune compartmentsSemantic proximity Read

Understanding and Modeling the Pathophysiology of Hydrocephalus: In Search of Better Treatment OptionsSemantic proximity Read

Early transcriptional and cellular abnormalities in choroid plexus of a mouse model of Alzheimer’s diseaseSemantic proximity Read

The Human and Rat Choroid Plexus Express Key Elements of the Neurosteroidogenesis PathwaySemantic proximity Read

Alterations in choroid plexus gene expression in Alzheimer’s disease provide inferences for CSF composition and dynamicsSemantic proximity Read

RNA-seq reveals transcriptomic differences in circadian-related genes of the choroid plexus in a preclinical chronic migraine modelSemantic proximity Read

Microvascular architecture and dynamics of the choroid plexus brain barrierSemantic proximity Read