Article

Choroid plexus sex differences in secretory signalling and immune compartments

2025-08-19

Abstract excerpt

The choroid plexus (ChP)-cerebrospinal fluid (CSF) axis is emerging as a key regulator of the brain environment. The ChP is a multi-functional structure, which forms the blood-CSF barrier, and acts as a sensor of inputs from the periphery and the brain, dynamically responding by modulating its secretome into the CSF. However, sex differences in the ChP have been little explored. Molecular profiling of the adult mo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f4813532-1bf9-5950-b745-3bec9bfb8037
DOI: 10.1101/2025.08.15.670566

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Choroid plexus sex differences in secretory signalling and immune compartmentsDOI 10.1101/2025.08.15.670566Read

A cellular and spatial map of the choroid plexus across brain ventricles and agesSemantic proximity Read

A Single-Cell Atlas of the Mouse Dural Meninges Reveals Pervasive Sex Differences Across Cellular CompartmentsSemantic proximity Read

Adult Mouse Leptomeninges Exhibit Regional and Age-related Cellular Heterogeneity Implicating Mental DisordersSemantic proximity Read

A Multi-omic Atlas of Human Choroid Plexus in Alzheimer’s DiseaseSemantic proximity Read

Early transcriptional and cellular abnormalities in choroid plexus of a mouse model of Alzheimer’s diseaseSemantic proximity Read

Effects of early life adversity on meningeal mast cells and proinflammatory gene expression in male and female <i>Mus musculus</i>Semantic proximity Read

Tissue-specific immune transcriptional signatures in the bordering tissues of the mouse brain and retinaSemantic proximity Read

Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexusSemantic proximity Read

The subcommissural organ regulates brain development via secreted peptidesSemantic proximity Read

Evolutionary development of embryonic cerebrospinal fluid composition and regulation: an open research field with implications for brain development and functionSemantic proximity Read

Alterations in choroid plexus gene expression in Alzheimer’s disease provide inferences for CSF composition and dynamicsSemantic proximity Read

Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammationSemantic proximity Read