Article

Proteomic signature of the Dravet syndrome in the genetic <i>Scn1a</i> -A1783V mouse model

2021-04-28

Abstract excerpt

<h4>Background</h4> Dravet syndrome is a rare, severe pediatric epileptic encephalopathy associated with intellectual and motor disabilities. Proteomic profiling in a mouse model of Dravet syndrome can provide information about the molecular consequences of the genetic deficiency and about pathophysiological mechanisms developing during the disease course. <h4>Methods</h4> A knock-in mouse model of Dravet syndro...

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Literature Corpus work: 3c2adc77-a6c1-5792-b235-6f727842e191
DOI: 10.1101/2021.04.27.441099

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