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Plasma proteomic architecture of incident valvular heart disease in the UK Biobank: discovery, genetic prioritization, and exploratory risk discrimination

2026-06-09

Abstract excerpt

<title>Abstract</title> <p>Background Valvular heart disease (VHD) is increasingly prevalent in aging populations, but the circulating proteomic features that precede incident disease remain incompletely characterized. We aimed to identify plasma proteins associated with incident VHD, prioritize genetically supported candidates, and assess the incremental value of proteomic information for risk discrimination. M...

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Literature Corpus work
3c202ee1-8a93-5d0b-90d1-c146a4609861
DOI
10.21203/rs.3.rs-9565765/v1
Open publication

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Plasma proteomic architecture of incident valvular heart disease in the UK Biobank: discovery, genetic prioritization, and exploratory risk discriminationDOI 10.21203/rs.3.rs-9565765/v1
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