Article
Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives.
The Lancet. Infectious diseases - 1 Mar 2018
Abel Laurent, Fellay Jacques, Haas David W, Schurr Erwin, Srikrishna Geetha, Urbanowski Michael, Chaturvedi Nimisha, Srinivasan Sudha, Johnson Daniel H, Bishai William R
Abstract excerpt
Tuberculosis is an ancient human disease, estimated to have originated and evolved over thousands of years alongside modern human populations. Despite considerable advances in disease control, tuberculosis remains one of the world's deadliest communicable diseases with 10 million incident cases and 1·8 million deaths in 2015 alone based on the annual WHO report, due to inadequate health service resources in...
Topics
- Antitubercular Agents
- Drug Resistance, Multiple, Bacterial
- Genetic Predisposition to Disease
- Humans
- Mycobacterium tuberculosis
- Pharmacogenetics
- Tuberculosis