Article

Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish

2020-12-30

Abstract excerpt

<title>Abstract</title> <p><bold><italic>Background</italic></bold>: Heparan sulfate proteoglycan 2 (<italic>HSPG2)</italic> encodes for perlecan, a large proteoglycan that plays an important role in cartilage formation, cell adhesion, and basement membrane stability. Mutations in <italic>HSPG2</italic> have been associated with Schwartz-Jampel Syndrome (SJS) and Dyssegmental Dysplasia Silverman-Handmaker Type (D...

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Literature Corpus work: 3ba82133-4c31-5996-be85-0b7474ffe338
DOI: 10.21203/rs.3.rs-27670/v3

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