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Article

HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas.

PloS one - 1 Jan 2012

Wiweger Malgorzata I, Zhao Zhe, van Merkesteyn Richard J P, Roehl Henry H, Hogendoorn Pancras C W

Abstract excerpt

Multiple Osteochondromas (MO; previously known as multiple hereditary exostosis) is an autosomal dominant genetic condition that is characterized by the formation of cartilaginous bone tumours (osteochondromas) at multiple sites in the skeleton, secondary bursa formation and impingement of nerves, tendons and vessels, bone curving, and short stature. MO is also known to be associated with arthritis, general pain,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22253766
DOI: 10.1371/journal.pone.0029734
PMCID: PMC3256178

Genes

EXT1
EXT2
FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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