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Wolf-Hirschhorn Syndrome-associated genes are enriched in motile neural crest and affect craniofacial development in <i>Xenopus laevis</i>

2018-11-15

Abstract excerpt

Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a microdeletion, on the short arm of chromosome four. In addition to pronounced intellectual disability, seizures, and delayed growth, WHS presents with a characteristic facial dysmorphism and varying prevalence of microcephaly, micrognathia, cartilage malformation in the ear and nose, and facial asym...

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Literature Corpus work
9a0b3c7e-ff51-5034-8b0c-0ff4b2d71c24
DOI
10.1101/471672
Open publication

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