Article

A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in <i>Dictyostelium</i>

2019-02-21

Abstract excerpt

Telomerase, particularly its main subunit, the reverse transcriptase, TERT, prevents DNA erosion during eukaryotic chromosomal replication, but also has poorly understood non-canonical functions. Here, in the model social amoeba Dictyostelium discoideum, we show that the protein encoded by tert has telomerase-like motifs and regulates, non-canonically, important developmental processes. Expression levels of wild...

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Literature Corpus work: 3b69fcf3-a19f-5f91-89cd-b9a565f8837f
DOI: 10.1101/556977

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