Article

Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors

2023-06-22

Abstract excerpt

<h4>Introduction</h4> Targeted gene editing is proposed as a therapeutic approach for numerous disorders, including neurological diseases. As the brain is organized into neural networks, it is critical to understand how anatomically connected structures are affected by genome editing. For example, neurons in the substantia nigra pars compacta (SNpc) project to the striatum, and the striatum contains neurons that...

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Literature Corpus work: 3b4c8882-af14-5e7f-9575-250c76941875
DOI: 10.1101/2023.06.21.542185

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