Article
DARPP-32 genomic fragments drive Cre expression in postnatal striatum.
Genesis (New York, N.Y. : 2000) - 1 May 2005
Bogush Alexey I, McCarthy Lois E, Tian Chai, Olm Vicki, Gieringer Tracy, Ivkovic Sanja, Ehrlich Michelle E
Abstract excerpt
To direct Cre-mediated recombination to differentiated medium-size spiny neurons (MSNs) of the striatum, we generated transgenic mice that express Cre recombinase under the regulation of DARPP-32 genomic fragments. In this reported line, recombination of an R26R reporter allele occurred postnatally in the majority of medium-size spiny neurons of the dorsal and ventral striatum (caudate nucleus and nucleus...
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