Article

ARID1B promotes DNA end resection via MDC1 and co-transactivation of DNA repair genes with c-MYC in small cell lung cancer

2026-02-10

Abstract excerpt

<title>Abstract</title> <p> AT-rich interactive domain-containing protein 1B (ARID1B) has been implicated in DNA damage repair, yet its precise molecular mechanisms and contributions to small cell lung cancer (SCLC) pathogenesis remain incompletely defined. In this study, analysis of clinical datasets revealed <italic>ARID1B</italic> overexpression in SCLC tissues and cell lines compared to normal lung or lung...

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Literature Corpus work: 3b414ca4-2987-5122-8275-ba43080732c2
DOI: 10.21203/rs.3.rs-8612664/v1

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