Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B cell neoplasias

28 Oct 2024

Abstract excerpt

γδ-T cells expansion correlates with treatment efficacy validated in a cohort of B-ALL (n = 18) and diffuse large B cell lymphoma (DLBCL) patients (n = 58). Our data provide insights into the complexity of T cell responses following CAR-T cell therapy and suggest drivers of immunotherapy response.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Single-cell and spatial transcriptomics
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39471818
DOI: 10.1016/j.xcrm.2024.101803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B cell neoplasiasPMID 39471818Read ↗

Integrative single-cell multi-omics of CD19-CAR <sup>pos</sup> and CAR <sup>neg</sup> T cells suggest drivers of immunotherapy response in B-cell neoplasiasSemantic proximity Read ↗

Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes.Semantic proximity Read ↗

A Multi-Omics Analysis of an Exhausted T Cells’ Molecular Signature in Pan-CancerSemantic proximity Read ↗

Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution.Semantic proximity Read ↗

Functional diversification and dynamics of CAR-T cells in patients with B-ALLSemantic proximity Read ↗

Distinct cellular dynamics associated with response to CAR-T therapy for refractory B-cell lymphomaSemantic proximity Read ↗

Immunogenomic landscape of hematological malignanciesSemantic proximity Read ↗

Integrative genomic analysis identifies unique immune environments associated with immunotherapy response in diffuse large B cell lymphomaSemantic proximity Read ↗

Single‐Cell RNA‐Seq of T Cells in B‐ALL Patients Reveals an Exhausted Subset with Remarkable HeterogeneitySemantic proximity Read ↗

Identification of clonally expanded Tγδ populations during CAR-T cell therapySemantic proximity Read ↗

Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALLSemantic proximity Read ↗

Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of <i>KMT2A</i> -rearranged leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.