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LSD1 Expression is Associated with Immune Exclusion and Hypoxia-Related Transcriptional Programs in Triple-Negative Breast Cancer

2026-08-26

Abstract excerpt

<title>Abstract</title> <p>Background Triple-negative breast cancer (TNBC) exhibits aggressive biology and heterogeneous immune infiltration. Lysine-specific demethylase 1 (LSD1/KDM1A) is an epigenetic regulator implicated in oncogenic transcriptional programs; however, its association with hypoxia signaling and immune exclusion in TNBC remains incompletely defined. Methods LSD1 expression was evaluated by immu...

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Literature Corpus work
3b0c532a-5a53-5167-af75-b9ddc56c6e0a
DOI
10.21203/rs.3.rs-9655879/v1
Open publication

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LSD1 Expression is Associated with Immune Exclusion and Hypoxia-Related Transcriptional Programs in Triple-Negative Breast CancerDOI 10.21203/rs.3.rs-9655879/v1
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