Article

The fitness cost of mis-splicing is the main determinant of alternative splicing patterns

2017-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Most eukaryotic genes are subject to alternative splicing (AS), which may contribute to the production of functional protein variants or to the regulation of gene expression, notably via nonsense-mediated mRNA decay (NMD). However, a fraction of splice variants might correspond to spurious transcripts, and the question of the relative proportion of splicing errors vs. functional splice variants...

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Literature Corpus work: 3ac2954a-f657-5623-82c2-c9cea67fd8cf
DOI: 10.1101/114215

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