Article

Isolation of RNA Aptamers Targeting HER-2-overexpressing Breast Cancer Cells Using Cell-SELEX

2009-08-20

Abstract excerpt

Ligand molecules that can recognize and interact with cancer cell surface marker proteins with high affinity and specificity should greatly aid the development of novel cancer diagnostics and therapeutics. HER-2/ErbB2/Neu (HER-2), a member of the epidermal growth factor receptor family, is specifically overexpressed on the surface of breast cancer cells and serves as both a useful biomarker and a therapeutic targe...

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Literature Corpus work: 3a8f0783-c538-5706-a6ab-022941e0db49
DOI: 10.5012/bkcs.2009.30.8.1827

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