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Article

A novel molecular marker of breast cancer stem cells identified by cell-SELEX method.

Cancer biomarkers : section A of Disease markers - 1 Jan 2015

Lu Min, Zhou Lei, Zheng Xiaohui, Quan Yi, Wang Xiaoli, Zhou Xinna, Ren Jun

Abstract excerpt

BACKGROUND: Breast cancer stem cells (CSCs) are thought to initiate mammary tumors and render them resistant to anti-cancer therapies. However, there are currently no ideal biomarkers to identify this minority population in breast cancer. OBJECTIVE: To find out the oligonucleotides with high specificity and affinity for mammosphere cells using a high capacity ssDNA library. METHODS: We used the cell-SELEX...

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Identifiers

PMID: 25519016
DOI: 10.3233/CBM-140450
PMCID: PMC12928526

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CD24
CD44

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