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Article

<i>In Vitro</i> Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells

1 Jun 2011

Abstract excerpt

The ErbB family (also referred to as HER/neu or HER) of receptor tyrosine kinases plays major roles in the formation and progression of human tumors. Amplification and/or overexpression of ErbB2 have been reported in numerous cancers, including breast, ovarian, stomach, bladder, salivary, and lung cancers. As ErbB2 has been used as a target for the treatment of advanced cancer, RNA aptamers for the extracellular...

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PMID: 21749294
DOI: 10.1089/nat.2011.0283

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