Article

Cancer-associated fibroblast compositions change with breast-cancer progression linking S100A4 and PDPN ratios with clinical outcome

2020-01-13

Abstract excerpt

Tumors are supported by cancer-associated fibroblasts (CAFs). CAFs are heterogeneous and carry out distinct cancer-associated functions. Understanding the full repertoire of CAFs and their dynamic changes could improve the precision of cancer treatment. CAFs are usually analyzed at a single time-point using specific markers, and it is therefore unclear whether CAFs display plasticity as tumors evolve. Here, we ana...

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Literature Corpus work: 3a6e0c79-9d5f-5097-9559-c73d964f408a
DOI: 10.1101/2020.01.12.903039

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