Article

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

2016-06-10

Abstract excerpt

Genetic association studies have identified 210 risk loci for inflammatory bowel disease 1–7 , which have revealed fundamental aspects of the molecular biology of the disease, including the roles of autophagy and Th17 cell signaling and development. We performed a genome-wide association study of 25,305 individuals, and meta-analyzed with published summary statistics, yielding a total sample size of 59,957 subjec...

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Literature Corpus work: 3a67b604-b124-58e2-8b4a-e8c4f6ae29d3
DOI: 10.1101/058255

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