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Article

Pathway-based Genome-wide Association Studies Reveal the Association Between Growth Factor Activity and Inflammatory Bowel Disease.

Inflammatory bowel diseases - 1 Jul 2016

Li Jin, Wei Zhi, Chang Xiao, Cardinale Christopher J, Kim Cecilia E, Baldassano Robert N, Hakonarson Hakon

Abstract excerpt

BACKGROUND: The inflammatory bowel diseases known as Crohn's disease (CD) and ulcerative colitis (UC) are related autoimmune conditions with a complex etiology composed of genetic and environmental factors. Genetic studies have revealed 200 susceptibility loci for inflammatory bowel diseases, but these only account for a small fraction of the genetic heritability of the disease. We employed pathway-based...

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Identifiers

PMID: 27104816
DOI: 10.1097/MIB.0000000000000785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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