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IKZF2-ERBB4 gene fusion leads to <i>ERBB4</i> overexpression in Anal Squamous Cell Carcinoma but with no benefit for ERBB4 inhibition

2024-12-03

Abstract excerpt

Anal squamous cell carcinoma (ASCC) is a rare tumour, but with increasing incidence for local and metastatic tumours. Current therapy is based on chemoradiotherapy, associated with immunotherapy in advanced stages, with frequent side effects, poor results in advanced stages and recurrence. New therapeutics, including targeted therapies, are then needed. In this context, we identified here a IKZF2 - ERBB4 gene fu...

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Literature Corpus work
3a3a33aa-8bbc-514a-a157-84d745e87ade
DOI
10.1101/2024.11.28.625910
Open publication

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IKZF2-ERBB4 gene fusion leads to <i>ERBB4</i> overexpression in Anal Squamous Cell Carcinoma but with no benefit for ERBB4 inhibitionDOI 10.1101/2024.11.28.625910
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