Article
Molecular and genomic characterisation of a panel of human anal cancer cell lines.
Cell death & disease - 18 Oct 2021
Guerra Glen R, Kong Joseph C, Millen Rosemary M, Read Matthew, Liu David S, Roth Sara, Sampurno Shienny, Sia Joseph, Bernardi Maria-Pia, Chittleborough Timothy J, Behrenbruch Corina C, Teh Jiasian, Xu Huiling, Haynes Nicole M, Yu Jiaan, Lupat Richard, Hawkes David, Di Costanzo Natasha, Tothill Richard W, Mitchell Catherine, Ngan Samuel Y, Heriot Alexander G, Ramsay Robert G, Phillips Wayne A
Abstract excerpt
Anal cancer is a rare disease that has doubled in incidence over the last four decades. Current treatment and survival of patients with this disease has not changed substantially over this period of time, due, in part, to a paucity of preclinical models to assess new therapeutic options. To address this hiatus, we set-out to establish, validate and characterise a panel of human anal squamous cell carcinoma (ASCC)...
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