Article
A growing family: adding mutated Erbb4 as a novel cancer target.
Cell cycle (Georgetown, Tex.) - 15 Apr 2010
Rudloff Udo, Samuels Yardena
Abstract excerpt
As the upward spiral of novel cancer gene discoveries and novel molecular compounds continues to accelerate, a repetitive theme in molecular drug development remains the lack of activity of initially promising agents when given to patients in clinical trials. It is however invigorating that a few targeted agents directed against a select group of a few 'cancer gene superfamilies' have escaped this all to common...
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