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Genetic Architecture, Developmental Mechanisms, and Genomic Applications in Left Ventricular Non-Compaction Cardiomyopathy (LVNC)

2025-09-08

Abstract excerpt

Left ventricular non-compaction cardiomyopathy (LVNC) is characterized by a thinned compact myocardium overlain by prominent trabeculations with deep recesses that communicate with the ventricular cavity. In normal development, the embryonic ventricle is “spongy”; trabeculation facilitates exchange before the coronary circulation forms, after which compaction transforms this scaffold into mature wall. This process...

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Literature Corpus work
4722ad19-5305-5a3f-bcdb-968e4b03e5d9
DOI
10.20944/preprints202509.0586.v1
Open publication

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