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Article

Left ventricular excessive trabeculation: pathophysiology, diagnostic challenges, and prognostic significance.

Heart failure reviews - 7 Jul 2026

Beltrami Matteo, Maestrini Viviana, Baritussio Anna, Netti Lucrezia, Colalillo Nicola, Di Franco Sonia, Palazzuoli Alberto

Abstract excerpt

Excessive trabeculation has been considered the morphological hallmark of left ventricular non-compaction (LVNC), traditionally viewed as a primary cardiomyopathy resulting from an arrest in myocardial compaction during embryonic development. However, more recent evidence suggests that excessive trabeculation of the left ventricle (LVET) may represent a phenotypic trait with heterogeneous etiologies, which can be...

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PMID: 42412251
DOI: 10.1007/s10741-026-10649-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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