Article

A role for glutathione in buffering excess intracellular copper in <i>Streptococcus pyogenes</i>

2020-05-15

Abstract excerpt

<h4>ABSTRACT</h4> Copper (Cu) is an essential metal for bacterial physiology but in excess it is bacteriotoxic. To limit Cu levels in the cytoplasm, most bacteria possess a transcriptionally-responsive system for Cu export. In the Gram-positive human pathogen Streptococcus pyogenes (Group A Streptococcus , GAS), this system is encoded by the copYAZ operon. In this study, we demonstrate that the site of GAS inf...

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Literature Corpus work: 39990cad-dbe7-5028-8199-ed4e0971d5e3
DOI: 10.1101/2020.05.14.095349

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