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Article

Mis-regulation of Zn and Mn homeostasis is a key phenotype of Cu stress in Streptococcus pyogenes.

Metallomics : integrated biometal science - 2 Nov 2023

Hong YoungJin, Mackenzie Eilidh S, Firth Samantha J, Bolton Jack R F, Stewart Louisa J, Waldron Kevin J, Djoko Karrera Y

Abstract excerpt

All bacteria possess homeostastic mechanisms that control the availability of micronutrient metals within the cell. Cross-talks between different metal homeostasis pathways within the same bacterial organism have been reported widely. In addition, there have been previous suggestions that some metal uptake transporters can promote adventitious uptake of the wrong metal. This work describes the cross-talk between...

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Copper
Homeostasis
Metals
Phenotype
Streptococcus pyogenes

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PMID: 37849243
DOI: 10.1093/mtomcs/mfad064
PMCID: PMC10644519

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