Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Manganese Homeostasis in Group A Streptococcus Is Critical for Resistance to Oxidative Stress and Virulence

25 Mar 2015

Abstract excerpt

UNLABELLED: Streptococcus pyogenes (group A Streptococcus [GAS]) is an obligate human pathogen responsible for a spectrum of human disease states. Metallobiology of human pathogens is revealing the fundamental role of metals in both nutritional immunity leading to pathogen starvation and metal poisoning of pathogens by innate immune cells. Spy0980 (MntE) is a paralog of the GAS zinc efflux pump CzcD. Through use...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Genetics and Biotechnology
Share to Neonatal and Maternal Infections
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25805729
DOI: 10.1128/mbio.00278-15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Manganese Homeostasis in Group A Streptococcus Is Critical for Resistance to Oxidative Stress and VirulencePMID 25805729Read ↗

Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniaeSemantic proximity Read ↗

Iron Efflux by PmtA Is Critical for Oxidative Stress Resistance and Contributes Significantly to Group A Streptococcus VirulenceSemantic proximity Read ↗

Cellular management of Zinc in group B <i>Streptococcus</i> supports bacterial resistance against metal intoxication and promotes disseminated infectionSemantic proximity Read ↗

Interplay between manganese and zinc homeostasis in the human pathogen Streptococcus pneumoniaeSemantic proximity Read ↗

The PerR-Regulated P1B-4-Type ATPase (PmtA) Acts as a Ferrous Iron Efflux Pump in Streptococcus pyogenes.Semantic proximity Read ↗

Managing Manganese: The Role of Manganese Homeostasis in Streptococcal PathogenesisSemantic proximity Read ↗

Manganese homeostasis and utilization in pathogenic bacteriaSemantic proximity Read ↗

PerR-Regulated Manganese Import Contributes to Oxidative Stress Defense in Streptococcus suisSemantic proximity Read ↗

Metal Homeostasis in Pathogenic StreptococciSemantic proximity Read ↗

Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of Staphylococcus aureusSemantic proximity Read ↗

ZccE is a Novel P-type ATPase That Protects <i>Streptococcus mutans</i> Against Zinc IntoxicationSemantic proximity Read ↗

Manganese uptake, mediated by SloABC and MntH, is essential for the fitness of <i>Streptococcus mutans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.