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Article

Pathogenic adaptations to host-derived antibacterial copper

1 Jan 2014

Abstract excerpt

Recent findings suggest that both host and pathogen manipulate copper content in infected host niches during infections. In this review, we summarize recent developments that implicate copper resistance as an important determinant of bacterial fitness at the host-pathogen interface. An essential mammalian nutrient, copper cycles between copper (I) (Cu(+)) in its reduced form and copper (II) (Cu(2+)) in its...

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PMID: 24551598
DOI: 10.3389/fcimb.2014.00003

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