Article
Ploidy dynamics and evolvability in fungi.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Dec 2016
Wertheimer Noa Blutraich, Stone Neil, Berman Judith
Abstract excerpt
Rapid responses to acute stresses are essential for stress survival and are critical to the ability of fungal pathogens to adapt to new environments or hosts. The rapid emergence of drug resistance is used as a model for how fungi adapt and survive stress conditions that inhibit the growth of progenitor cells. Aneuploidy and loss of heterozygosity (LOH), which are large-scale genome shifts involving whole...
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