Article

A mouse model of sporadic Alzheimer’s disease with elements of major depression

2024-01-04

Abstract excerpt

Animals after bulbectomy are often used as a model of major depression or sporadicAlzheimer’s disease and, hence, the status of this model is still disputable. To elucidate the nature of alterations in the expression of the genome after the operation we analyzed transcriptomes (RNA-seq data) of the cortex, hippocampus, and cerebellum of olfactory bulbectomized (OBX) mice. Analysis of the functional significance of...

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Literature Corpus work: 39464cb5-123a-586a-aec3-46a6720a6531
DOI: 10.21203/rs.3.rs-3781115/v1

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