Article

Behavioural and transcriptomic characterization of the comorbidity between Alzheimer’s disease and Major Depression

2020-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Major Depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer’s disease (AD). Despite both diseases having a robust genetic component, the common transcriptomic signature remains unknown. In this regard, we investigated the cognitive and emotional responses in 3- and 6-month-old in APP/PSEN1-Tg mutant mice, before β-amyloid...

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Literature Corpus work: 0819aec5-0920-5325-a87e-11c919185448
DOI: 10.1101/2020.07.31.231159

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