Back to search

Article

Genome-wide screen identifies novel factors for surface protein cross-wall trafficking and cell envelope homeostasis in <i>Staphylococcus aureus</i>

2025-11-04

Abstract excerpt

Cell wall anchored surface proteins are integral components of the Gram-positive bacterial cell envelope and are vital for bacterial survival in different environmental niches. The trafficking of many surface proteins carrying a YSIRK/G-S signal peptide is synchronized with cell envelope biogenesis during cell division, whereby YSIRK proteins traffic to the septal membrane and anchor to septal peptidoglycan (cross...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
39343877-cb93-50b4-b29d-b8e5ec493680
DOI
10.1101/2025.11.03.686427
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genome-wide screen identifies novel factors for surface protein cross-wall trafficking and cell envelope homeostasis in <i>Staphylococcus aureus</i>DOI 10.1101/2025.11.03.686427
The ClpX chaperone controls the <i>Staphylococcus aureus</i> cell cycle but can be bypassed by β-lactam antibioticsSemantic proximity
LytN, a murein hydrolase in the cross-wall compartment of Staphylococcus aureus, is involved in proper bacterial growth and envelope assembly.Semantic proximity
MsrR contributes to cell surface characteristics and virulence in<i>Staphylococcus aureus</i>Semantic proximity
Mapping the Pathways to StaphylococcalPathogenesis by Comparative SecretomicsSemantic proximity
ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus.Semantic proximity
Inactivation of the monofunctional peptidoglycan glycosyltransferase SgtB allows <i>Staphylococcus aureus</i> to survive in the absence of lipoteichoic acidSemantic proximity
The cell surface proteome of <i>Staphylococcus aureus</i>Semantic proximity
Comparative Tn-Seq reveals common daptomycin resistance determinants in <i>Staphylococcus aureus</i> despite strain-dependent differences in essentiality of shared cell envelope genesSemantic proximity
Functional and Proteomic Dissection of the Contributions of CodY, SigB and the Hibernation Promoting Factor HPF to Interactions of Staphylococcus aureus USA300 with Human Lung Epithelial CellsSemantic proximity
Chemical Probes Reveal an Extraseptal Mode of Cross-Linking in Staphylococcus aureusSemantic proximity
Screening a library of temperature-sensitive mutants to identify secretion factors in Staphylococcus aureusSemantic proximity
The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in <i>Staphylococcus aureus</i>Semantic proximity
Select a neighboring publication to make it the new centre.