Article
ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus.
Molecular microbiology - 1 Oct 2010
Frankel Matthew B, Wojcik Brandon M, DeDent Andrea C, Missiakas Dominique M, Schneewind Olaf
Abstract excerpt
The human pathogen Staphylococcus aureus requires cell wall anchored surface proteins to cause disease. During cell division, surface proteins with YSIRK signal peptides are secreted into the cross-wall, a layer of newly synthesized peptidoglycan between separating daughter cells. The molecular determinants for the trafficking of surface proteins are, however, still unknown. We screened mutants with non-redundant...
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