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Inactivation of the monofunctional peptidoglycan glycosyltransferase SgtB allows <i>Staphylococcus aureus</i> to survive in the absence of lipoteichoic acid

2018-04-30

Abstract excerpt

The cell wall of Staphylococcus aureus is composed of peptidoglycan and the anionic polymers lipoteichoic acid (LTA) and wall teichoic acid. LTA is required for growth and normal cell morphology in S. aureus. Strains lacking LTA are usually only viable when grown under osmotically stabilizing conditions or after the acquisition of compensatory mutations. LTA negative suppressor strains with inactivating mutation...

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Literature Corpus work
3363b951-3bc4-51cb-b111-8f5d3ac64f28
DOI
10.1101/311282
Open publication

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