Article

Impulse model-based differential expression analysis of time course sequencing data

2017-03-05

Abstract excerpt

The global gene expression trajectories of cellular systems in response to developmental or environmental stimuli often follow the prototypic single-pulse or state-transition patterns which can be modeled with the impulse model. Here we combine the continuous impulse expression model with a sequencing data noise model in ImpulseDE2, a differential expression algorithm for time course sequencing experiments such as...

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Literature Corpus work: 38bd3f41-d51b-565c-a31c-c6b4367f3291
DOI: 10.1101/113548

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