Article

Hallmarks of <i>Alpha</i> - and <i>Betacoronavirus</i> non-structural protein 7+8 complexes

2020-09-30

Abstract excerpt

Coronaviruses infect many different species including humans. The last two decades have seen three zoonotic coronaviruses with SARS-CoV-2 causing a pandemic in 2020. Coronaviral non-structural proteins (nsp) built up the replication-transcription complex (RTC). Nsp7 and nsp8 interact with and regulate the RNA-dependent RNA-polymerase and other enzymes in the RTC. However, the structural plasticity of nsp7+8 comple...

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Identifiers and source

Literature Corpus work: 388ef103-18dd-58cc-ae96-607ecf41f82a
DOI: 10.1101/2020.09.30.320762

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