Article
DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells.
The Journal of biological chemistry - 21 Jul 2006
Bader Sonya, Kortholt Arjan, Snippe Helena, Van Haastert Peter J M
Abstract excerpt
Dictyostelium discoideum cells possess multiple cyclic nucleotide phosphodiesterases that belong either to class I enzymes that are present in all eukaryotes or to the rare beta-lactamase class II. We describe here the identification and characterization of DdPDE4, the third class I enzyme of Dictyostelium. The deduced amino acid sequence predicts that DdPDE4 has a leader sequence, two transmembrane segments, and...
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