Article

STAT3 Suppresses The AMPKα-ULK1-Dependent Induction of Autophagy In Glioblastoma Cells

2021-10-11

Abstract excerpt

Despite advances in molecular characterization, glioblastoma (GBM) remains the most lethal type of brain tumor with high mortality rates in both pediatric and adult patients. The signal transducer and activator of transcription 3 (STAT3), is an important oncogenic driver of GBM. Although STAT3 reportedly plays a role in autophagy of some cells, its role in cancer cell autophagy remains unclear. In this study, we f...

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Literature Corpus work: 387adfc5-be03-578e-a50a-4325428b99bf
DOI: 10.21203/rs.3.rs-953023/v1

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